Biological Tissue Sample Studies: New Biomarkers and Laboratory Models to Understand Disease Mechanisms and Screen Potential Treatments
Patients and families we work with generously donate blood samples, spinal fluid samples, skin samples, and eventually the brain after a person passes away. Using these samples, we have worked with many collaborators to discover new biomarkers of these diseases that may be helpful in diagnosis or monitoring and to use these biological samples to help generate new kinds of models that can be used in the laboratory to better understand the biological and chemical abnormalities associated with these diseases. These laboratory models can also be used to screen new potential treatments for abnormalities in the cellular pathways that enable our brain cells to function properly.
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